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Our body carries some volume of antinuclear antibodies, which are essential to keep the immune system strong. However, any variant in the antibodies can affect our health. In case of any symptoms, an anti-nuclear antibody test is conducted to detect antinuclear antibodies in your bloodstream. These antibodies are proteins produced by your immune system to protect against harmful invaders like viruses and bacteria. However, antinuclear antibodies mistakenly target your body’s healthy cells. They are called "antinuclear" because they attack the nucleus, the control center of the cell, responsible for regulating key functions. If the anti-ANA test report is positive, the doctor would suggest a panel of tests to identify specific antibodies.
The anti-ANA test is conducted to detect, measure, and assess the presence of antinuclear antibodies in a blood sample. The anti-nuclear antibody factor test helps healthcare providers identify autoimmune disorders and can offer valuable insights that may aid in determining the specific type of autoimmune condition you may have. Some of the autoimmune disorder symptoms considered are- Polymyositis & dermatomyositis, Fatigue, and others.
The ANA test report is provided in two forms-
● Titer Reading- These are expressed as ratios, commonly such as 1:40, 1:80, 1:160, 1:320, or 1:640. Higher titers result in higher disease activity
● Patterns: In this, the results may also include specific staining patterns, such as homogeneous, speckled, centromere, and others.
To begin the procedure, the healthcare provider wraps an elastic band around your upper arm. A needle is then carefully inserted into the vein, and blood is drawn into an attached airtight vial or tube. After enough blood has been collected, the elastic band is removed.
For infants or young children, a lancet—a small, sharp instrument—may be used to prick the skin. It is quick, and the baby won’t face any pain.
There are no special preparations or perquisites that patients need to follow for the anti-nuclear antibody test. You can continue with your normal diet routine before the test. You need to provide a complete medical history to know if you have any allergies and avoid medical complications.
And: ANA testing is usually done based on a doctor's recommendation. It involves taking a blood sample from a vein in your arm. You will be provided with the result of examining your blood.
Ans: You may undergo this test if you're experiencing symptoms that could indicate an autoimmune disorder, such as unexplained joint pain, fever, or chest discomfort. One of the most common reasons for ordering this test is the suspicion of systemic lupus erythematosus.
Ans: The test involves minimal risk. You might experience mild pain or bruising at the site where the needle was inserted, but these symptoms usually fade quickly.