Vitamin D 1,25 Dihydroxy Test Overview

The Vitamin D 1,25 is a specialized test conducted to measure the overall level of 1,25-dihydroxyvitamin D (calcitriol), the active form of vitamin D in the body. When vitamin D enters the body from dietary sources like fish, eggs, and dairy products or through sunlight hitting the skin, a series of actions begins to turn it into a nutrient that the body can use.

After entering the body, the vitamin is transformed into 25-hydroxyvitamin D by the liver. The ideal time to check the body's levels of vitamin D is after this conversion. Kidney problems, anomalies of the parathyroid gland, some types of cancer, and problems with bone metabolism can all be linked to abnormal levels.

When is the Vitamin D 1,25 Dihydroxy Test Prescribed?

There are different reasons for the vitamin D 1,25 Dihydroxy Test. It helps to evaluate disorders affecting kidney function, calcium regulation, parathyroid activity, and vitamin D metabolism.

Osteoporosis, which causes bones to weaken and become more susceptible to injuries, osteomalacia, which causes bones to become soft and easily fractured, and rickets, which causes weak bones in youngsters due to a lack of vitamin D, are some bone health conditions that fall under this category.

There are other situations when doctors prescribe the vitamin D 1, 25 dihydroxy test:

To check abnormal blood levels of phosphorus or calcium.
When there is a suspicion of renal illness or reduced kidney function.
To assess parathyroid gland diseases.
To identify specific bone conditions like osteomalacia or rickets.
If there are signs like muscle weakness, bone pain, or repeated fractures.

Components of Vitamin D 1, 25 Dihydroxy Test

Doctors, when interpreting the report, check the parameter to measure the overall concentration of calcitriol in the bloodstream. Calcitriol is essential for supporting neuromuscular function, encouraging bone mineralization, and preserving the balance of calcium and phosphorus.

If the report shows low levels, then it could be a sign of kidney failure, hypoparathyroidism, or problems with vitamin D metabolism. Similarly, elevated levels could be linked to hyperparathyroidism, granulomatous illnesses, or some types of cancer.

Procedure and Preparation

The overall procedure for the Vitamin D 1, 25 Dihydroxy Test is quick and easy. The lab clinician would collect a blood sample and send it for the test. No special preparation is required to undergo the test. However, patients should provide information about their medical history and whether they are taking any supplements.

Vitamin D 1, 25 - Dihydroxy in Thrissur

Vitamin D 1, 25 - Dihydroxy in Thrissur

V0029

Daily

No Special Preparation Required

24 Hours

₹3,520

Parameters

Copyright © 2026 Aster Clinical Lab LLP. All Rights Reserved