*Genexpert with Rifampicin resistance * Culture AFB, Rapid
It is a simple PCR test which is used to detect Mycobacterium tuberculosis (MTB) the causative organism of tuberculosis (TB). The other purpose of this test is to find whether the bacteria is responsive or unresponsive to a drug called rifampicin. It is a quick and accurate test which is useful in TB patients for early diagnosis and providing precise treatment.
Tuberculosis is a very common disease in India caused by a bacterium called Mycobacterium tuberculosis. It is a type of acid-fast bacilli (AFB). This disease is highly infectious (spreads from one person to another through tiny droplets) and predominantly affects the lungs. Tuberculosis is more common in people infected with HIV (human immunodeficiency virus).
The common symptoms of active pulmonary (lungs) TB are:
The other less common sites which can be infected with tuberculosis are spine, brain, intestine, genitals, kidneys, joints, liver etc. Diagnosis of tuberculosis is done by the following methods:
Tuberculosis treatment includes intake of many drugs which have to be taken for prolonged period. If not taken properly it may lead to development of drug resistant tuberculosis also called MDR TB. The common drugs used for treatment of tuberculosis are:
Your health care provider may prescribe this test for diagnosis of TB and to look for Rifampicin resistance in MTB. It is also useful for diagnosis of TB in those individuals whose microscopy report is negative for TB.
Various samples like Sputum, Pus, Tissue, CSF, body fluids, urine can be processed on Genexpert to detect MTB.
This test is done with the help of disposable cartridge wherein sample from the person is mixed with reagent and cartridge containing this mixture is placed in the machine. It is a type of nucleic acid amplification/ PCR test. Its result should be interpreted with clinical, radiographic and other test findings.
Result can be Mycobacterium tuberculosis detected or not detected.
If Mycobacterium tuberculosis is detected, resistance to rifampicin -detected, not detected or indeterminate will also be reported.